DermaFreeze 365 Review


The wrinkle treatment DermaFreeze 365 claims to be an effective “wrinkle relaxer” that is suitable for use on any area of the body. The product was developed by the California-based company Woodbridge Labs, who have been selling DermaFreeze 365 since 1996. This product features a GABA-Biox complex that, they claim, will act as a miracle muscle relaxer anywhere that you have wrinkles. The theory behind DermaFreeze 365 is that repetitive muscle contractions will eventually lead to fine lines and wrinkles.

Interestingly, the manufacturers for DermaFreeze 365 also pedal an extensive and seemingly random line of products, including treatments for dry mouth, sun spots, spider veins, do-it-yourself microdermabrasion sets and more. We’re not sure if this is more or less reassuring. Many of these products seem to be “patent pending.”

Product Details

DermaFreeze 365 makes some pretty big claims, promising dramatic results (50%+ wrinkle reduction!) in minutes. Our policy towards many wrinkle products that we look at is if they really sound too good to be true, then they just might be. Sending up further red flags, DermaFreeze 365 touts its “miracle” ingredient Biox, but offers no details about it on their official website.

DermaFreeze 365 is meant to be applied to a clean, dry face. Massage the cream gently into the face, paying special attention to problem areas like around the eyes or mouth. For best results, let the cream absorb for at least ten minutes, then apply a moisturizer of your choice.

The full list of active ingredients found in DermaFreeze 365 includes: Water, Glyceryl Stearate, Sesame (Sesamum Indicum) Seed Oil, Caprylic/Capric Triglyceride, PEG-150 Distearate, GABA-Biox (Glycyrrhiza Glabra Root Extract and Gamma Amino Butyric Acid), Cetearyl Alcohol, Butylene Glycol, Panax Ginseng Root Extract, Ethoxydiglycol, Xanthan Gum, Eugenol, Gynostemma Pentaphylium Extract Orchid (Orchis Maculata) Flower Extract, Propylene Glycol, Tetrasodium EDTA, Methylparaben, Propylparaben, Diazolidinyl Urea, Phenoxyethanol, Bismuth Oxychloride.

The Good

  • Product is available from numerous retail locations.
  • Product is relatively inexpensive.

The Bad

  • No details of “miracle” active ingredients are given.
  • No clinical studies or product trials are given.
  • Product includes multiple parabens, which have been linked to contact dermatitis in some users.
  • Product claims strikes us as a little “too good to be true.”

The Bottom Line

We wish that we thought DermaFreeze 365 would do what the makers promise. If it could really guarantee a 50%+ wrinkle decrease minutes after application, we’d run around shouting “Hallelujah!” But realistically, we don’t see anything in DermaFreeze 365’s ingredient list that would be the catalyst for such dramatic results. It doesn’t help that the product manufacturers are frustratingly vague about key active ingredients and product studies. Additionally, if a company really had discovered the fountain of youth, you would think they’d offer a free sample or a money-back guarantee, just til they got their users hooked. This does not seem to be the case with DermaFreeze 365. If the product manufactures would take a little time to provide potential users with some more information, we might reconsider our opinion on this one, but until we learn more we can’t get too excited about it.


  1. amy March 4, 2015
  2. Caroline Cast. December 17, 2012
  3. april May 27, 2012
  4. april May 27, 2012
  5. kate October 16, 2011
  6. deanna June 2, 2011
  7. eleni May 2, 2011
  8. Iliana 09, 02-2010 September 2, 2010
  9. Gigi July 10, 2010
  10. Sherry June 2, 2010
  11. Peggy May 11, 2010

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